David, here is an interesting fact concerning the south, states rights and federalism:
in the lifetime of many confederate soldiers, who had sacrificed so much for states rights, and during the very era that the Lost Cause movement was resurging and statues all over the south were being erected in public squares to honor the Patriots of States Rights, the southern states, with Mississippi and Virginia leading the nation and South Carolina number 5, were the among the very first to ratify the 18th constitutional amendment:

In order they were:

Mississippi (January 8, 1918)
Virginia (January 11, 1918)
Kentucky (January 14, 1918)
North Dakota (January 25, 1918)
South Carolina (January 29, 1918)
Maryland (February 13, 1918)
Montana (February 19, 1918)
Texas (March 4, 1918)
Delaware (March 18, 1918)
South Dakota (March 20, 1918)
Massachusetts (April 2, 1918)
Arizona (May 24, 1918)
Georgia (June 26, 1918)
Louisiana (August 3, 1918)[5]
Florida (November 27, 1918)
Michigan (January 2, 1919)
Ohio (January 7, 1919)
Oklahoma (January 7, 1919)
Idaho (January 8, 1919)
Maine (January 8, 1919)
West Virginia (January 9, 1919)
California (January 13, 1919)
Tennessee (January 13, 1919)
Washington (January 13, 1919)
Arkansas (January 14, 1919)
Kansas (January 14, 1919)
Alabama (January 15, 1919)
Colorado (January 15, 1919)
Iowa (January 15, 1919)
New Hampshire (January 15, 1919)
Oregon (January 15, 1919)
Nebraska (January 16, 1919)
North Carolina (January 16, 1919)
Utah (January 16, 1919)
Missouri (January 16, 1919)
Wyoming (January 16, 1919)

Only 36 were needed, the rest of the states, none southern, passed after the fact or did not approve the measure. The former confederate states were unanimous in approving. The amendment ratified in 1919.

I think this tends to show that the issue of states rights vs federal power was a moot point to the people of the south as far back as 1919. At least it seems as long as the underlying issue was one they approved of, the south had no objection whatsoever to the feds setting policy for the entire country and trumping states rights. States rights took a back seat in the south in 1919, as it does today with southern conservatives calling for federal marriage amendments etc in the present day.