"IF" Virginia and North Carolina had NOT ratified the Constitution and remained independent, bearing in mind that many of the people in North Carolina had strong family ties with Virginia having been that many Virginians had immigrated to North Carolina, it would have been likely that those two states would have formed their own country/compact.

If Virginia and North Carolina had formed such a compact, it would have been a logical assumption that their territories of Kentucky and Tennessee would have joined that Compact also instead of joining the United States. That would have formed a country that reached from the Atlantic to the Mississippi River and would in effect totally isolated Georgia and South Carolina from the rest of the northern United States. That in turn would have also influenced the future of the states of Alabama and Mississippi.

Florida probably would have joined with Georgia and South Carolina to form the third state in the "southern United States", "IF" Georgia and South Carolina had not already seceeded from the United States and join with this "Virginia Confederation" by that time.

There probably would not have been a Louisiana Purchase either as George Washington and Thomas Jefferson would probably have been the Presidents of the "Virginia Confederaction". Then again it might have happened and the western states would have joined the Virginia Confederation.

So the point of all this is, is that even "IF" the slavery clauses were placed into the Constitution to entice the Southern States to ratify the Constitution, the end result for the future developement, even the future continued existance of the United States would not have been a bad thing in the long run.