This what I know, he was a private in Company B, 16th Mississippi, from 1861 to 1862 and was discharged for disability in Virginia.

His service records end there, however, his wife's application for pension says he enlisted in 1862 into Company F, 4th Mississippi Cavalry in Mississippi and died near Clinton, Louisiana in March of 1863.
This is the second soldier from the 16th that was released from the infantry in Virginia only to show up later in the Cavalry in Mississippi. My question is there a possibility that he died in combat or did he die of other causes.

The Fourth had several companies detached doing picket work or patrols around Louisiana and Mississippi during early 1863.

His wife named his company commander as Captain Blue, and his regimental commanders as Major McLaurin, and Colonel Wilborn... I have found references that closely match these names.

He is also referenced as being doctor, this can be found in the Simpson County Confederate records.