1) Isaac Edwards, Blount County, age 34 in 1860 - Co C, 29th Alabama Regiment.
2) Isaac E Edwards, Bibb County, age 18 in 1860 - Co H, 29th Alabama Regiment. He appears on the 1870 census of Baker County (later Chilton).
3) Isaac Edwards, Shelby County, age 33 in 1860 - Camp of Instruction, Talladega.

Isaac [F or C] Edwards, Capt Jos W Guilford's Henry County Reserves, a company raised when the Alabama militia reorganized in 1864. in 1860 was age 11, a resident of Lawrenceville AL.
Isaac Edwards, Co D, Ready's Battalion, a temporary command organized from men at Camp of Instruction, Notasulga AL. Could be Isaac Edwards who appears on the 1866 state census and 1870 U S cenus for Randolph County, age 41 in 1870. Could also be Isaac P Edwards of Helicon, Pike County, no service found, age 12 in 1860 [born Mar 1847].