According to this site there was a skirmish that took place on Bayou Pierre near Willow Springs.
http://members.fortunecity.com/thegunny1/bayou_pierre_ms_2may63.htm
I also came across this site that states J. J. Harper and Mrs. O. B. Harper of Rocky Springs were victims of the 1878 yellow fever epidemic.
http://claibornecountyms.org/yellow1878.html
Hope this helps.