Dr. Massey, an excellent idea indeed insofar as checking with the University of Pennsylvania Medical College. Ironcially my great great grandfather was also a grad of a medical college in Ohio in that same year 1857. He had a class photo however the medical college did NOT. I think there were something like eight grads in the class of 1857 at his medical college. It leads me to believe that the grads kept their photo's but for whatever reason the college's did NOT prior to the WBTS at least that is what my research thus far has determined. It would be possible to find out who the others were in that class of Dr. Holloway's and maybe their descendants might still have a class photo in one of their attics? The best of luck to you sir.