Stephen,
Problems of one sort or another were bound to arise as long as a predominantly agricultural region and people and a predominantly industrial region and people coexist side-by-side in an interdendant relationship.
The two regions are the antitheses of each other in just too many ways to permit peaceful, long-term coexistance.
I see parallels in overlapping or adjacent tectonic plates - they impose stress upon each other until they finally reach the breaking point - then quakes and tsunamis occur - can't be avoided.